Yvonne Achermann

 

Projects

Propionibacterium species (currently named as Cutibacterium sp): Prevention, diagnosis and treatment

The use of orthopedic implants has been increasing steadily in the last 50 years, but despite considerable technological advances including perioperative antimicrobial prophylaxis, implant-associated infections remain a serious complication. These infections are caused by bacteria in the biofilm on the implant surfaces.
Implant-associated infections such as periprosthetic joint infections or spinal implant-associated infections are a feared complication after orthopedic surgery. These infections are usually difficult to treat, because microorganisms persist in biofilms on the orthopedic implant surface. Therefore, it would be desirable to prevent these infections.
Cutibacterium spp. are bacteria which normally colonize the human skin but they can also cause invasive infections in presence of an implant such as shoulder or hip prosthetic joint infections (Achermann et al., CMR, 2015, Achermann et al. Clin Infect Dis 2018;66(1): 54-63).
An improved prevention or an early diagnosis is the main objective of this research area to reduce morbidity in implant-associated infections caused by Propionibacterium sp. (currently named as Cutibacterium sp).

Projects

Time
Subject
Grants
Involved research people
04/2019 (ongoing)
Effects of photodynamic therapy on the human inguinal skin microbiome to improve antiseptic effect.
Vontobel foundation
Galderma
Isabelle Waldmann
Julia Prinz
08/2018 (ongoing)
Role of rifampin in Cutibacterium sp. periprosthetic joint infection (PJI) – a multi-center study supported by the ESCMID.
supported by the European Society of Clinical Microbiology and Infectious Diseases
Kusejko Katharina
Jaime Esteban
10/2018 (ongoing)
Skin antisepsis to reduce Cutibacterium avidum colonization as a risk factor for periprosthetic joint infections.
Swiss Life Jubiläumsstiftung
Steven Maurer
09/2017
Prospective observational cohort study on periprosthetic joint infections at the Balgrist University Clinic
Balgrist Foundation
Octavian Andronic
Cornelia Issler
Fabienne Walser
03/2020
Clostridium difficile at the USZ: a quality control study
Pending
Tina Badinksi
12/2016 (ongoing)
The role of Cutibacterium acnes infection in intervertebral disc inflammation (with K. Würtz).
CABMM start up
Bettina Schmid

 

Our team is involved in several national and international research projects about prevention, diagnostic and treatment of orthopedic infections not listed above. Yvonne Achermann is a board member of the European study group of the implant-associated infections (ESGIAI), member of the "Expertengruppe Infektionen der Schweizerischen Gesellschaft für Orthopädie und Traumatologie", and Swiss Country Delegate of the European Bone and Joint Infection Society (EBJIS). 

Contact

PD Dr. med. Yvonne Achermann
Division of Infectious Diseases and Hospital Epidemiology
University Hospital Zurich
Rämistrasse 100
CH-8091 Zürich
yvonne.achermann@usz.ch


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